Make 42 dangles by threading assorted 8mm, 6mm and 4mm round crystals and pearls on headpins and turning a simple or wrapped loop above each one (reference how to on wrapped loop).
Two:
Center a 4mm crystal or pearl (not one of the dangles) on your beading wire.
Three:
Center a 4mm crystal or pearl (not one of the dangles) on your beading wire.
Four:
String the remaining dangles on either side in groups of seven dangles tapering the sizes down to the 4mm dangles. Separate each set of 7 dangles with a 4mm bead.
Five:
String the 4mm bicones and pearls on each side to complete the necklace.